Regional quantification of cerebral venous oxygenation from MRI susceptibility mapping during hypercapnia
نویسندگان
چکیده
Regional quantification of cerebral venous oxygenation from MRI susceptibility mapping during hypercapnia Audrey P Fan, Karleyton C Evans, Jeffrey N Stout, Bruce R Rosen, and Elfar Adalsteinsson Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, Psychiatry, Massachusetts General Hospital, Boston, MA, United States, Health Sciences and Technology, Harvard-MIT, Cambridge, MA, United States
منابع مشابه
Quantification of dynamic changes in cerebral venous oxygenation with MR phase imaging at 1.9 T.
A double-echo magnetic resonance (MR) phase imaging method was used to measure the time-dependent changes in regional cerebral venous blood oxygenation during neural stimulation. Our results showed that a finger opposition task induced an absolute increase of blood oxygenation level of deltaY = 0.16+/-0.05 (n = 6), which was measured in the small veins located in the left central sulcus. It was...
متن کاملDevelopment, testing, and application of quantitative oxygenation imaging from magnetic susceptibility by MRI
The healthy brain consumes 20% of total oxygen used by the body under normal conditions. Continuous oxygen delivery to neural tissue is needed to maintain normal brain function and viability. Reliable measurements of brain oxygenation can provide critical information to diagnose and manage diseases in which this oxygen supply is disturbed, including stroke and tumor. In acute stroke, for instan...
متن کاملCorrection: Correction: Cerebral Hemodynamic Changes of Mild Traumatic Brain Injury at the Acute Stage
Mild traumatic brain injury (mTBI) is a significant public health care burden in the United States. However, we lack a detailed understanding of the pathophysiology following mTBI and its relation to symptoms and recovery. With advanced magnetic resonance imaging (MRI), we can investigate brain perfusion and oxygenation in regions known to be implicated in symptoms, including cortical gray matt...
متن کاملRole of Local Nerves and Prostaglandins in Regulation of Basal Blood Flow and Hypercapnic Vasodilatation of Cerebral Blood Vessels in the Rabbit
The mechanisms underlying cerebral vasodilatation during hypercapnia are not fully understood. To examine the role of nerves and prostaglandins in the regulation of basal blood flow and in hypercapnia-induced vasodilatation in the cerebral blood vessels of rabbit.Cerebral blood flow was measured by laser Doppler flow-meter in 18 NZW rabbits anesthetized with sodium pentobarbital. Tetrodetoxin ...
متن کاملA generalized procedure for calibrated MRI incorporating hyperoxia and hypercapnia.
Calibrated MRI techniques use the changes in cerebral blood flow (CBF) and blood oxygenation level-dependent (BOLD) signal evoked by a respiratory manipulation to extrapolate the total BOLD signal attributable to deoxyhemoglobin at rest (M). This parameter can then be used to estimate changes in the cerebral metabolic rate of oxygen consumption (CMRO(2)) based on task-induced BOLD and CBF signa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013